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1

Modeling of Human Hepatic and Gastrointestinal Ethanol Metabolism With Kinetic Mechanism-Based Full Rate Equations of the Component Alcohol Dehydrogenase Isozymes and Allozymes

Chi, Yu-Chou, Lee, Shou-Lun, Lee, Yung-Ping, Lai, Ching-Long, Yin, Shih-Jiun

Journal:

Chemical Research in Toxicology

Year:

2018

Language:

english

File:

PDF, 540 KB

english, 2018

2

[IEEE 2015 IEEE International Symposium on Circuits and Systems (ISCAS) - Lisbon, Portugal (2015.5.24-2015.5.27)] 2015 IEEE International Symposium on Circuits and Systems (ISCAS) - An 8-bit column-shared SAR ADC for CMOS image sensor applications

Lin, Jin-Yi, Chang, Kwuang-Han, Kao, Chen-Che, Lo, Shih-Chin, Chen, Yan-Jiun, Lee, Pei-Chen, Chen, Chi-Hui, Yin, Chin, Hsieh, Chih-Cheng

Year:

2015

Language:

english

File:

PDF, 557 KB

english, 2015

3

Ethanol oxidation and the inhibition by drugs in human liver, stomach and small intestine: Quantitative assessment with numerical organ modeling of alcohol dehydrogenase isozymes

Chi, Yu-Chou, Lee, Shou-Lun, Lai, Ching-Long, Lee, Yung-Pin, Lee, Shiao-Pieng, Chiang, Chien-Ping, Yin, Shih-Jiun

Journal:

Chemico-Biological Interactions

Year:

2016

Language:

english

File:

PDF, 1.64 MB

english, 2016

4

No Sex and Age Influence on the Expression Pattern and Activities of Human Gastric Alcohol and Aldehyde Dehydrogenases

Ching-Long Lai, You-Chen Chao, Yi-Chyan Chen, Chin-Shya Liao, Mei-Chun Chen, Yee-Chun Liu, Shih-Jiun Yin

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2000

Language:

english

File:

PDF, 101 KB

english, 2000

5

Functional Assessment of Human Alcohol Dehydrogenase Family in Ethanol Metabolism: Significance of First-Pass Metabolism

Shou-Lun Lee, Gar-Yang Chau, Chung-Tay Yao, Chew-Wun Wu, Shih-Jiun Yin

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2006

Language:

english

File:

PDF, 193 KB

english, 2006

6

Alcohol and Aldehyde Dehydrogenases in Human Esophagus: Comparison With the Stomach Enzyme Activities

Shih-Jiun Yin, Fang-Ju Chou, Shu-Feng Chao, Sho-Feng Tsai, Chin-Shya Liao, Sung-Ling Wang, Chew-Wun Wu, Shih-Chun Lee

Journal:

Alcoholism: Clinical and Experimental Research

Year:

1993

Language:

english

File:

PDF, 1.03 MB

english, 1993

7

Alcohol abuse and related factors in Asia

Chen, Chiao-Chicy, Yin, Shih-Jiun

Journal:

International Review of Psychiatry

Year:

2008

Language:

english

File:

PDF, 281 KB

english, 2008

8

Effects of Acupuncture on Serum Cortisol Level and Dopamine Beta-hydroxylase Activity in Normal Chinese

Lee, Shih-Ching, Yin, Shih-Jiun, Lee, Mei-Ling, Tsai, Wen-Jr, Sim, Cho-Boon

Journal:

The American Journal of Chinese Medicine

Year:

1982

Language:

english

File:

PDF, 319 KB

english, 1982

9

Polymorphism of alcohol and aldehyde dehydrogenase genes and alcoholic cirrhosis in chinese patients

You-Chen Chao, Shian-Ren Liou, Ying-Ying Chung, Hung-Shang Tang, Chung-Te Hsu, Ting-Kai Li, Shih-Jiun Yin

Journal:

Year:

1994

Language:

english

File:

PDF, 785 KB

english, 1994

10

Immunochemical features in the classification of human alcohol dehydrogenase family

Shiao-Pieng Lee, Chien-Ping Chiang, Shou-Lun Lee, Yi-Jan Hsia, Tzu-Ling Chuang, Jau-Chen Lin, San-Chi Liang, Shih Nieh, Shih-Jiun Yin

Journal:

Year:

2006

Language:

english

File:

PDF, 283 KB

english, 2006

11

Establishment of steady-state metabolism of ethanol in perfused rat liver: the quantitative analysis using kinetic mechanism-based rate equations of alcohol dehydrogenase

Chung-Tay Yao, Ching-Long Lai, Hsiu-Shan Hsieh, Chin-Wen Chi, Shih-Jiun Yin

Journal:

Year:

2010

Language:

english

File:

PDF, 281 KB

english, 2010

12

Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents

Chih-Jung Kuo, Jiun-Jie Shie, Jim-Min Fang, Guei-Rung Yen, John T.-A. Hsu, Hun-Ge Liu, Sung-Nain Tseng, Shih-Cheng Chang, Ching-Yin Lee, Shin-Ru Shih, Po-Huang Liang

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 645 KB

english, 2008

13

Synthesis and antipicornavirus activity of (R)- and (S)-1-[5-(4′-chlorobiphenyl-4-yloxy)-3-methylpentyl]-3-pyridin-4-yl-imidazolidin-2-one

Jyh-Haur Chern, Chih-Shiang Chang, Chia-Liang Tai, Yen-Chun Lee, Chung-Chi Lee, Iou-Jiun Kang, Ching-Yin Lee, Shin-Ru Shih

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 372 KB

english, 2005

14

Isatin-β-thiosemicarbazones as potent herpes simplex virus inhibitors

Iou-Jiun Kang, Li-Wen Wang, Tsu-An Hsu, Andrew Yueh, Chung-Chi Lee, Yen-Chun Lee, Ching-Yin Lee, Yu-Sheng Chao, Shin-Ru Shih, Jyh-Haur Chern

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 694 KB

english, 2011

15

Thin-layer chromatographic separation of imidazole compounds and its application to radiotracing studies of brain histidine metabolism

Shih-Ching Lee, Shih-Jiun Yin

Journal:

Journal of Chromatography A

Year:

1976

Language:

english

File:

PDF, 448 KB

english, 1976

16

Genetic polymorphism and activities of human lung alcohol and aldehyde dehydrogenases: Implications for ethanol metabolism and cytotoxicity

Shih-Jiun Yin, Chin-Shya Liao, Chun-Mei Chen, Fa-Ti Fan, Shih-Chun Lee

Journal:

Biochemical Genetics

Year:

1992

Language:

english

File:

PDF, 695 KB

english, 1992

17

Genetic variation at twentythree microsatellite loci in sixteen human populations

Ranjan Deka, Mark D. Shriver, Ling Mei Yu, Elisa Mueller Heidreich, Li Jin, Yixi Zhong, Stephen T. Mcgarvey, Shyam Swarup Agarwal, Clareann H. Bunker, Tetsuro Miki, Joachim Hundrieser, Shih-Jiun Yin,

Journal:

Journal of Genetics

Year:

1999

Language:

english

File:

PDF, 193 KB

english, 1999

18

Avian Reovirus activates a novel proapoptotic signal by linking Src to p53

Lin Ping-Yuan, Liu Hung-Jen, Lai Meng-Jiun, Yu Feng-Ling, Hsu Hsue-Yin, Lee Jeng-Woei, Shih Wen-Ling

Journal:

Year:

2006

Language:

english

File:

PDF, 1.50 MB

english, 2006

19

Relation of genotypes of alcohol metabolizing enzymes and mortality of liver diseases in patients with alcohol dependence

Chiao-Chicy Chen, Chian-Jue Kuo, Shang-Ying Tsai, Shih-Jiun Yin

Journal:

Addiction Biology

Year:

2004

Language:

english

File:

PDF, 63 KB

english, 2004

20

Alcohol Metabolism and Cardiovascular Response in an Alcoholic Patient Homozygous for the ALDH2*2 Variant Gene Allele

Yi-Chyan Chen, Ru-Band Lu, Giia-Sheun Peng, Ming-Fang Wang, Hsu-Kun Wang, Huei-Chen Ko, Yue-Cune Chang, Jang-Jih Lu, Ting-Kai Li, Shih-Jiun Yin

Journal:

Alcoholism: Clinical and Experimental Research

Year:

1999

Language:

english

File:

PDF, 828 KB

english, 1999

21

No Association Between DRD2 Locus and Alcoholism After Controlling the ADH and ALDH Genotypes in Chinese Han Population

Jia-Fu Lee, Ru-Band Lu, Huei-Chen Ko, Fong-Ming Chang, Shih-Jiun Yin, Andrew J. Pakstis, Kenneth K. Kidd

Journal:

Alcoholism: Clinical and Experimental Research

Year:

1999

Language:

english

File:

PDF, 841 KB

english, 1999

22

Genetic and Environmental Influences on Alcohol Metabolism in Humans

Ting-Kai Li, Shih-Jiun Yin, David W. Crabb, Sean O'Connor, Vijay A. Ramchandani

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2001

Language:

english

File:

PDF, 94 KB

english, 2001

23

Expression Pattern, Ethanol-Metabolizing Activities, and Cellular Localization of Alcohol and Aldehyde Dehydrogenases in Human Pancreas: Implications for Pathogenesis of Alcohol-Induced Pancreatic Injury

Chien-Ping Chiang, Chew-Wun Wu, Shiao-Pieng Lee, Chia-Chi Chung, Chi-Wei Wang, Shou-Lun Lee, Shin Nieh, Shih-Jiun Yin

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2009

Language:

english

File:

PDF, 702 KB

english, 2009

24

Possible Interaction of Alcohol Dehydrogenase and Aldehyde Dehydrogenase Genes With the Dopamine D2 Receptor Gene in Anxiety-Depressive Alcohol Dependence

San-Yuan Huang, Wei-Wen Lin, Huei-Chen Ko, Jia-Fu Lee, Tso-Jen Wang, Yuan-Hwa Chou, Shih-Jiun Yin, Ru-Band Lu

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2004

Language:

english

File:

PDF, 117 KB

english, 2004

25

Expression pattern, ethanol-metabolizing activities, and cellular localization of alcohol and aldehyde dehydrogenases in human large bowel: association of the functional polymorphisms of ADH and ALDH genes with hemorrhoids and colorectal cancer

Chien-Ping Chiang, Shu-Wen Jao, Shiao-Pieng Lee, Pei-Chi Chen, Chia-Chi Chung, Shou-Lun Lee, Shin Nieh, Shih-Jiun Yin

Journal:

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

26

Substrate specificity of human and yeast aldehyde dehydrogenases

Ming-Fang Wang, Chih-Li Han, Shih-Jiun Yin

Journal:

Chemico-Biological Interactions

Year:

2009

Language:

english

File:

PDF, 144 KB

english, 2009

27

Polymorphism of ethanol-metabolism genes and alcoholism: Correlation of allelic variations with the pharmacokinetic and pharmacodynamic consequences

Yi-Chyan Chen, Giia-Sheun Peng, Ming-Fang Wang, Tien-Ping Tsao, Shih-Jiun Yin

Journal:

Chemico-Biological Interactions

Year:

2009

Language:

english

File:

PDF, 393 KB

english, 2009

28

Oxidation of methanol, ethylene glycol, and isopropanol with human alcohol dehydrogenases and the inhibition by ethanol and 4-methylpyrazole

Shou-Lun Lee, Hsuan-Ting Shih, Yu-Chou Chi, Yeung-Pin Li, Shih-Jiun Yin

Journal:

Chemico-Biological Interactions

Year:

2011

Language:

english

File:

PDF, 470 KB

english, 2011

29

Recommended nomenclature for the vertebrate alcohol dehydrogenase gene family

Gregg Duester, Jaume Farrés, Michael R Felder, Roger S Holmes, Jan-Olov Höög, Xavier Parés, Bryce V Plapp, Shih-Jiun Yin, Hans Jörnvall

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 210 KB

english, 1999

30

Human class IV alcohol dehydrogenase: kinetic mechanism, functional roles and medical relevance

Shih-Jiun Yin, Chu-Fang Chou, Ching-Long Lai, Shou-Lun Lee, Chih-Li Han

Journal:

Chemico-Biological Interactions

Year:

2003

Language:

english

File:

PDF, 229 KB

english, 2003

31

Contribution to first-pass metabolism of ethanol and inhibition by ethanol for retinol oxidation in human alcohol dehydrogenase family : Implications for etiology of fetal alcohol syndrome and alcohol-related diseases

Chih-Li Han, Chin-Shya Liao, Chew-Wun Wu, Ching-Long Hwong, An-Rong Lee, Shih-Jiun Yin

Journal:

Year:

1998

Language:

english

File:

PDF, 172 KB

english, 1998

32

Genetic Polymorphism and Activities of Human Colon Alcohol and Aldehyde Dehydrogenases: No Gender and Age Differences

Shih-Jiun Yin, Chin-Shya Liao, Ye-Chan Lee, Chew-Wun Wu, Shu-Wen Jao

Journal:

Alcoholism: Clinical and Experimental Research

Year:

1994

Language:

english

File:

PDF, 752 KB

english, 1994

33

Low Frequency of the ADH2*2 Allele among Atayal Natives of Taiwan with Alcohol Use Disorders

Holly R. Thomasson, David W. Crabb, Howard J. Edenberg, Ting-Kai Li, Hai-Gwo Hwu, Chiao-Chicy Chen, Eng-Kung Yeh, Shih-Jiun Yin

Journal:

Alcoholism: Clinical and Experimental Research

Year:

1994

Language:

english

File:

PDF, 433 KB

english, 1994

34

Cytochrome P4502E1 Genotypes, Alcoholism, and Alcoholic Cirrhosis in Han Chinese and Atayal Natives of Taiwan

Lucinda G. Carr, Im S. Yi, Ting-Kai Li, Shih-Jiun Yin

Journal:

Alcoholism: Clinical and Experimental Research

Year:

1996

Language:

english

File:

PDF, 435 KB

english, 1996

35

Primary structure and functional properties of cobra (Naja naja naja) venom Kunitz-type trypsin inhibitor

Jawed SHAFQAT, Obaid U. BEG, Shih-Jiun YIN, Zafar H. ZAIDI, Hans JÖRNVALL

Journal:

Year:

1990

Language:

english

File:

PDF, 381 KB

english, 1990

36

Pseudomonas 3β-hydroxysteroid dehydrogenase : Primary structure and relationships to other steroid dehydrogenases

Shih-Jiun YIN, Nikolaos VAGELOPOULOS, Gunilla LUNDQUIST, Hans JÖRNVALL

Journal:

Year:

1991

Language:

english

File:

PDF, 540 KB

english, 1991

37

Structural features of stomach aldehyde dehydrogenase distinguish dimeric aldehyde dehydrogenase as a ‘variable’ enzyme ‘Variable’ and ‘constant’ enzymes within the alcohol and aldehyde dehydrogenase families

Shih-Jiun Yin, Nikolaos Vagelopoulos, Sung-Ling Wang, Hans Jörnvall

Journal:

Year:

1991

Language:

english

File:

PDF, 711 KB

english, 1991

38

The metabolic role of human ADH3 functioning as ethanol dehydrogenase

Shou-Lun Lee, Ming-Fang Wang, An-I Lee, Shih-Jiun Yin

Journal:

Year:

2003

Language:

english

File:

PDF, 126 KB

english, 2003

39

Linkage Disequilibrium at the ADH2 and ADH3 Loci and Risk of Alcoholism

Michael Osier, Andrew J. Pakstis, Judith R. Kidd, Jia-Fu Lee, Shih-Jiun Yin, Huei-Chen Ko, Howard J. Edenberg, Ru-Band Lu, Kenneth K. Kidd

Journal:

The American Journal of Human Genetics

Year:

1999

Language:

english

File:

PDF, 503 KB

english, 1999

40

Interaction between the Functional Polymorphisms of the Alcohol-Metabolism Genes in Protection against Alcoholism

Chiao-Chicy Chen, Ru-Band Lu, Yi-Chyan Chen, Ming-Fang Wang, Yue-Cune Chang, Ting-Kai Li, Shih-Jiun Yin

Journal:

The American Journal of Human Genetics

Year:

1999

Language:

english

File:

PDF, 134 KB

english, 1999

41

Genetic polymorphism and activities of human lung alcohol and aldehyde dehydrogenases: Implications for ethanol metabolism and cytotoxicity

Shih-Jiun Yin,Chin-Shya Liao,Chun-Mei Chen,Fa-Ti Fan…

Journal:

Biochemical Genetics

Year:

1992

Language:

english

File:

PDF, 695 KB

english, 1992

42

Expression Pattern, Ethanol-Metabolizing Activities, and Cellular Localization of Alcohol and Aldehyde Dehydrogenases in Human Small Intestine

Chien-Ping Chiang, Chew-Wun Wu, Shiao-Pieng Lee, Ji-Lin Ho, Shou-Lun Lee, Shin Nieh, Shih-Jiun Yin

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2012

Language:

english

File:

PDF, 657 KB

english, 2012

43

Inhibition of human alcohol and aldehyde dehydrogenases by cimetidine and assessment of its effects on ethanol metabolism

Lai, Ching-Long, Li, Yeung-Pin, Liu, Chiu-Ming, Hsieh, Hsiu-Shan, Yin, Shih-Jiun

Journal:

Chemico-Biological Interactions

Year:

2013

Language:

english

File:

PDF, 587 KB

english, 2013

44

Inhibition of human alcohol and aldehyde dehydrogenases by acetaminophen: Assessment of the effects on first-pass metabolism of ethanol

Lee, Yung-Pin, Liao, Jian-Tong, Cheng, Ya-Wen, Wu, Ting-Lun, Lee, Shou-Lun, Liu, Jong-Kang, Yin, Shih-Jiun

Journal:

Year:

2013

Language:

english

File:

PDF, 807 KB

english, 2013

45

Expression and activities of class IV alcohol dehydrogenase and class III aldehyde dehydrogenase in human mouth

Dong, Yuan-Jang, Peng, Tzi-Kang, Yin, Shih-Jiun

Journal:

Year:

1996

Language:

english

File:

PDF, 714 KB

english, 1996

46

Treatment results and prognostic factors in resectable hepatocellular carcinoma—Results from a local general hospital

Wei, Chang-Kuo, Tsai, Shiang-Jiun, Yin, Wen-Yao, Chang, Chun-Ming, Chiou, Wen-Yen, Lee, Moon-Sing, Su, Yu-Chieh, Lin, Hon-Yi, Hung, Shih-Kai

Journal:

Tzu Chi Medical Journal

Year:

2014

Language:

english

File:

PDF, 463 KB

english, 2014

47

Selective carboxymethylation of cysteine-174 of the .beta.2.beta.2 and .beta.1.beta.1 human liver alcohol dehydrogenase isoenzymes by iodoacetate

Bosron, William F., Yin, Shih Jiun, Dwulet, Francis E., Li, Ting Kai

Journal:

Year:

1986

Language:

english

File:

PDF, 783 KB

english, 1986

48

Human liver alcohol dehydrogenase: purification and kinetic characterization of the .beta.2.beta.2, .beta.2.beta.1, .alpha..beta.2, and .beta.2.gamma.1 "Oriental" isoenzymes

Yin, Shih Jiun, Bosron, William F., Magnes, Leslie J., Li, Ting Kai

Journal:

Year:

1984

Language:

english

File:

PDF, 2.59 MB

english, 1984

49

[IEEE 2010 International Symposium on VLSI Design, Automation and Test (VLSI-DAT) - Hsin Chu, Taiwan (2010.04.26-2010.04.29)] Proceedings of 2010 International Symposium on VLSI Design, Automation and Test - Design of on-chip bus with OCP interface

Chin-Yao Chang,, Yi-Jiun Chang,, Kuen-Jong Lee,, Jen-Chieh Yeh,, Shih-Yin Lin,, Jui-Liang Ma,

Year:

2010

Language:

english

File:

PDF, 206 KB

english, 2010

50

Oxidative Status in Patients with Alcohol Dependence: A Clinical Study in Taiwan

Peng, Fu-Chuo, Tang, Sheng-Hui, Huang, Ming-Chi, Chen, Chiao-Chicy, Kuo, Tsung-Li, Yin, Shih-Jiun

Journal:

Journal of Toxicology and Environmental Health

Year:

2005

Language:

english

File:

PDF, 130 KB

english, 2005